Bern Open Repository and Information System (BORIS)
Article . 2020 . Peer-reviewed
Data sources: Bern Open Repository and Information System (BORIS)
Inactivation-mimicking block of the epithelial calcium channel TRPV6
NIH| Structure and Finction of AMPA subtype ionotropic glutamate receptors ,
NIH| Single-particle cryo-EM characterization of AMPA receptor functional states ,
FCT| LA 3 ,
NSF| NSF/MCB-BSF: Collaborative Research: Towards development of the structural determinants of the Glutamate receptor gating regulation by auxiliary membrane anchored proteins ,
NIH| Pixel Array Detector for X-ray Crystallography ,
NIH| Structure and function of Transient Receptor Potential channels ,
FWF| Mechanistic evaluation of a TRPV6 Ca2+channel inhibitor ,
NIH| National Resource for Automated Molecular Microscopy ,
NIH| NE-CAT: A Resource for Advanced Macromolecular Crystallography
Authors: Rajesh Bhardwaj; Sonja Lindinger; Arthur Neuberger; Kirill D. Nadezhdin; Appu K. Singh; Micael R. Cunha; Isabella Derler; +5 Authors
Rajesh Bhardwaj; Sonja Lindinger; Arthur Neuberger; Kirill D. Nadezhdin; Appu K. Singh; Micael R. Cunha; Isabella Derler; Gergely Gyimesi; Jean-Louis Reymond; Matthias A. Hediger; Christoph Romanin; Alexander I. Sobolevsky;
Inactivation-mimicking block of the epithelial calcium channel TRPV6
Abstract
Small-molecule piperazine derivatives mimic inactivation by calmodulin to selectively and potently block TRPV6 channels.
Country
Switzerland
Related Organizations
- COLUMBIA UNIVERSITY HEALTH SCIENCES
- Indian Institute of Technology Kanpur India
- Columbia University United States
- Columbia University United States
- Indian Institutes of Technology India
Keywords
Cryoelectron Microscopy, TRPV Cation Channels, 610 Medicine & health, Calmodulin, 540 Chemistry, 570 Life sciences; biology, Humans, Calcium, Calcium Channels, Research Articles
Cryoelectron Microscopy, TRPV Cation Channels, 610 Medicine & health, Calmodulin, 540 Chemistry, 570 Life sciences; biology, Humans, Calcium, Calcium Channels, Research Articles
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citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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NIH| Structure and Finction of AMPA subtype ionotropic glutamate receptors, NIH| Single-particle cryo-EM characterization of AMPA receptor functional states, FCT| LA 3, NSF| NSF/MCB-BSF: Collaborative Research: Towards development of the structural determinants of the Glutamate receptor gating regulation by auxiliary membrane anchored proteins
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