Analysis of Drosophila cardiac hypertrophy by microcomputerized tomography for genetic dissection of heart growth mechanisms
Copyright policy )Analysis of Drosophila cardiac hypertrophy by microcomputerized tomography for genetic dissection of heart growth mechanisms
Genetic analysis of Drosophila cardiac hypertrophy holds immense potential for the discovery of new therapeutic targets to prevent and treat heart failure. This potential has been hindered by a lack of rapid and effective methods for analyzing heart size in flies. Here, we demonstrate that analysis of the Drosophila heart with microcomputerized tomography yields accurate and highly reproducible heart size measurements that can be used to analyze heart growth and cardiac hypertrophy in Drosophila.
- Uniformed Services University of the Health Sciences United States
- University of Wyoming United States
Drosophila melanogaster, ORAI1 Protein, ras Proteins, Animals, Drosophila Proteins, Cardiomegaly, Heart, Calcium Signaling, Stromal Interaction Molecule 1, X-Ray Microtomography
Drosophila melanogaster, ORAI1 Protein, ras Proteins, Animals, Drosophila Proteins, Cardiomegaly, Heart, Calcium Signaling, Stromal Interaction Molecule 1, X-Ray Microtomography
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).7 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!