Phylogenetic Perspectives in Innate Immunity
Copyright policy )Phylogenetic Perspectives in Innate Immunity
The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent data have highlighted similarities between pathogen recognition, signaling pathways, and effector mechanisms of innate immunity in Drosophila and mammals, pointing to a common ancestry of these defenses. In addition to its role in the early phase of defense, innate immunity in mammals appears to play a key role in stimulating the subsequent, clonal response of adaptive immunity.
- French National Centre for Scientific Research France
- Massachusetts General Hospital United States
- European Molecular Biology Laboratory Germany
- Institute for Molecular and Cellular Biology France
- Harvard University United States
Mammals, Models, Immunological, Proteins, Infections, Immunity, Innate, Insect Vectors, Culicidae, Immunity, Active, Phagocytosis, Animals, Humans, Drosophila, Phylogeny
Mammals, Models, Immunological, Proteins, Infections, Immunity, Innate, Insect Vectors, Culicidae, Immunity, Active, Phagocytosis, Animals, Humans, Drosophila, Phylogeny
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