Name: Herpes Simplex Virus Encephalitis: Toll-Free Access to the Brain
Creator: Leib, David A.
Keywords: Central Nervous System, Cancer Research, Immunology and Microbiology(all), Induced Pluripotent Stem Cells, Brain, Encephalitis, Humans, Simplexvirus, Herpesvirus 1, Human, Molecular Biology

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2012 English Publisher:Elsevier BVJournal:Cell Host & Microbe, volume 12, pages 731-732 (issn: 1931-3128,

Authors: Leib, David A.;

doi: 10.1016/j.chom.2012.11.005

pmid: 23245315

pmc: PMC6932744

Herpes Simplex Virus Encephalitis: Toll-Free Access to the Brain

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Abstract

Herpes simplex encephalitis (HSE) is a devastating infection of the central nervous system (CNS). Lafaille et al. (2012) show that susceptibility to HSE is due to mutations in Toll-like receptor response pathways that directly reduce the intrinsic resistance of neurons and other cells in the CNS to HSV infection.

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Dartmouth College
United States

Keywords

Central Nervous System, Cancer Research, Immunology and Microbiology(all), Induced Pluripotent Stem Cells, Brain, Encephalitis, Humans, Simplexvirus, Herpesvirus 1, Human, Molecular Biology, Toll-Like Receptor 3

8 Research products, page 1 of 1

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