Placental expression of the nuclear receptors for oxysterols LXRα and LXRβ during mouse and human development
Copyright policy )Placental expression of the nuclear receptors for oxysterols LXRα and LXRβ during mouse and human development
AbstractOntogenesis and localization expression of genes encoding for the nuclear receptors for oxysterols (lxrα and lxrβ) were investigated in human and mouse placenta during gestation. Both mRNAs were detectable in the placentation throughout the gestation (from 7 days postcoitum and 6th week of gestation in mouse and human, respectively) by Northern blots or RT‐PCR experiments. Lxrα showed a higher accumulation in the mouse yolk sac. In situ hybridization pointed a specific expression of lxrα in the human amniotic membranes. © 2005 Wiley‐Liss, Inc.
- French National Centre for Scientific Research France
- Howard Hughes Medical Institute United States
- Biomolécules : Conception, Isolement, Synthèse France
- Inserm France
- Clermont Université France
Adult, Placenta, Embryonic Development, Receptors, Cytoplasmic and Nuclear, Cell Line, Mice, [SDV.CAN] Life Sciences [q-bio]/Cancer, Pregnancy, [SDV.EE.SANT] Life Sciences [q-bio]/Ecology, environment/Health, Animals, Humans, Amnion, RNA, Messenger, Fluorescent Antibody Technique, Indirect, In Situ Hybridization, Liver X Receptors, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, [SDV.BDD.GAM] Life Sciences [q-bio]/Development Biology/Gametogenesis, [SDV.BDLR.RS] Life Sciences [q-bio]/Reproductive Biology/Sexual reproduction, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Regulation, Developmental, Blotting, Northern, Orphan Nuclear Receptors, DNA-Binding Proteins, [SDV.BBM.MN] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular Networks [q-bio.MN], Female
Adult, Placenta, Embryonic Development, Receptors, Cytoplasmic and Nuclear, Cell Line, Mice, [SDV.CAN] Life Sciences [q-bio]/Cancer, Pregnancy, [SDV.EE.SANT] Life Sciences [q-bio]/Ecology, environment/Health, Animals, Humans, Amnion, RNA, Messenger, Fluorescent Antibody Technique, Indirect, In Situ Hybridization, Liver X Receptors, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, [SDV.BDD.GAM] Life Sciences [q-bio]/Development Biology/Gametogenesis, [SDV.BDLR.RS] Life Sciences [q-bio]/Reproductive Biology/Sexual reproduction, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Regulation, Developmental, Blotting, Northern, Orphan Nuclear Receptors, DNA-Binding Proteins, [SDV.BBM.MN] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular Networks [q-bio.MN], Female
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