Genetic variants (chr. 6) from Old World Schistosoma mansoni exomes

Name: Genetic variants (chr. 6) from Old World Schistosoma mansoni exomes
Creator: Chevalier, Frédéric D.
Keywords: exome data, Schistosome, https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=6183, variant calling file

Research datakeyboard_double_arrow_right Dataset 15 May 2019Publisher:Zenodo

Authors: Chevalier, Frédéric D.;

doi: 10.5281/zenodo.2850876 , 10.5281/zenodo.2850875

Genetic variants (chr. 6) from Old World Schistosoma mansoni exomes

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Abstract

Variant calling file (VCF) produced from exome libraries of Schistosoma mansoni (bloodfluke) samples from the Old Wold (West Africa (Senegal, Niger), East Africa (Tanzania), and Middle East (Oman)). One sample form the New World (Caribbean (HR9)) was added for comparison. The variants were called on the 3 Mb of chromosome 6 centered on the SmSULT-OR gene. This gene is involved in resistance to the drug oxamniquine (OXA). The aim of the related article was to investigate the origin of OXA resistant mutations in the New Wolrd by identifying sequence variation in SmSULT-OR in S. mansoni from the Old World, where OXA has seen minimal usage.

For technical details, please see the related article.

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Texas Biomedical Research Institute
United States

Keywords

exome data, Schistosome, https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=6183, variant calling file

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