E-cadherin-mediated adhesion is not the founding event of epithelial cell polarity in Drosophila
pmid: 15866027
E-cadherin-mediated adhesion is not the founding event of epithelial cell polarity in Drosophila
Formation of a polarized epithelial layer is a fundamental step during the development of multicellular animals. This process involves the coordinated action of adhesion molecules, actin remodeling and spatial organization of membrane traffic. A recent article describes a new hierarchy for the development of epithelial polarity in the early Drosophila embryo. Bazooka, a Par-3 homolog, is properly localized in the absence of adherens junctions, indicating that the formation of epithelial junctions is not the founding event of epithelial polarization.
Mammals, Cell Polarity, Epithelial Cells, Adherens Junctions, Cadherins, Models, Biological, Cell Adhesion, Animals, Drosophila, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Cell Adhesion Molecules
Mammals, Cell Polarity, Epithelial Cells, Adherens Junctions, Cadherins, Models, Biological, Cell Adhesion, Animals, Drosophila, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Cell Adhesion Molecules
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