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Science Translational Medicine
Article . 2011 . Peer-reviewed
Data sources: Crossref
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Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development

Authors: Jian, Wu; Hanno, Matthaei; Anirban, Maitra; Marco, Dal Molin; Laura D, Wood; James R, Eshleman; Michael, Goggins; +12 Authors

Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development

Abstract

A mutation in the gene GNAS serves as a marker for pancreatic cysts that can progress to become invasive adenocarcinomas, guiding therapy.

Keywords

Adult, Male, Cyst Fluid, High-Throughput Nucleotide Sequencing, DNA, Middle Aged, Adenocarcinoma, Mucinous, Clone Cells, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins, Mutation, Chromogranins, GTP-Binding Protein alpha Subunits, Gs, ras Proteins, Humans, Female, Neoplasm Invasiveness, Pancreatic Cyst, Aged, Carcinoma, Pancreatic Ductal

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    730
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 0.1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 0.1%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
730
Top 0.1%
Top 1%
Top 0.1%
bronze