Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development
Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development
A mutation in the gene GNAS serves as a marker for pancreatic cysts that can progress to become invasive adenocarcinomas, guiding therapy.
- Memorial Sloan Kettering Cancer Center United States
- DePaul University United States
- Indiana University United States
- Johns Hopkins University United States
- Indiana University – Purdue University Indianapolis United States
Adult, Male, Cyst Fluid, High-Throughput Nucleotide Sequencing, DNA, Middle Aged, Adenocarcinoma, Mucinous, Clone Cells, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins, Mutation, Chromogranins, GTP-Binding Protein alpha Subunits, Gs, ras Proteins, Humans, Female, Neoplasm Invasiveness, Pancreatic Cyst, Aged, Carcinoma, Pancreatic Ductal
Adult, Male, Cyst Fluid, High-Throughput Nucleotide Sequencing, DNA, Middle Aged, Adenocarcinoma, Mucinous, Clone Cells, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins, Mutation, Chromogranins, GTP-Binding Protein alpha Subunits, Gs, ras Proteins, Humans, Female, Neoplasm Invasiveness, Pancreatic Cyst, Aged, Carcinoma, Pancreatic Ductal
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