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Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Feb 2022 English Publisher:Elsevier BVJournal:Acta Pharmaceutica Sinica B, volume 12, pages 581-599 (issn: 2211-3835, Copyright policy )Funded by:UKRI | Digitally Connected Suppl..., UKRI | Agile Quantum Safe Commun...
Authors: Shenghua Gao; Tianguang Huang; Letian Song; Shujing Xu; Yusen Cheng; Srinivasulu Cherukupalli; Dongwei Kang; +5 Authors

doi: 10.1016/j.apsb.2021.08.027

pmid: 34485029

pmc: PMC8405450

Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors

Abstract

Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection. Herein, we briefly provide a concise report on the medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors with representative examples in different strategies from the medicinal chemistry perspective.

Related Organizations
Keywords

SARS-CoV-2, Antiviral drugs, Medicinal chemistry strategies, COVID-19, Therapeutics. Pharmacology, RM1-950, Review, Drug design

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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
46
Top 1%
Top 10%
Top 1%
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