Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane
Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane
Toxoplasma is an intracellular pathogen which resides and replicates inside a membrane-bound vacuole in infected cells. This vacuole is modified by both parasite and host proteins which participate in a variety of host-parasite interactions at this interface, including nutrient exchange, effector transport, and immune modulation.
- Stanford University United States
- Broad Institute United States
- Harvard University United States
quantitative proteomics, Endosomal Sorting Complexes Required for Transport, proximity-labeling, Calcium-Binding Proteins, Protozoan Proteins, Membrane Proteins, Cell Cycle Proteins, Intracellular Membranes, Microbiology, QR1-502, Host-Parasite Interactions, DNA-Binding Proteins, Protein Transport, Vacuoles, Humans, Receptors, Chemokine, Apoptosis Regulatory Proteins, Toxoplasma, Toxoplasmosis, Research Article
quantitative proteomics, Endosomal Sorting Complexes Required for Transport, proximity-labeling, Calcium-Binding Proteins, Protozoan Proteins, Membrane Proteins, Cell Cycle Proteins, Intracellular Membranes, Microbiology, QR1-502, Host-Parasite Interactions, DNA-Binding Proteins, Protein Transport, Vacuoles, Humans, Receptors, Chemokine, Apoptosis Regulatory Proteins, Toxoplasma, Toxoplasmosis, Research Article
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