The expression of DAZL1 in the ovary of the human female fetus

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2000 English Publisher:Elsevier BVJournal:Fertility and Sterility, volume 73, pages 627-630 (issn: 0015-0282,

Authors: M Y, Tsai; S Y, Chang; H Y, Lo; I H, Chen; F J, Huang; F T, Kung; Y J, Lu;

doi: 10.1016/s0015-0282(99)00544-0

pmid: 10689024

The expression of DAZL1 in the ovary of the human female fetus

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Abstract

To determine whether DAZL1 is expressed in human fetal ovarian tissue.The presence of DAZL1 expression was determined by reverse transcriptase polymerase chain reaction (RT-PCR).Academic tertiary care medical center and research unit of university.Five female abortuses between the 19th and 22nd week of gestational age.Fetal ovarian tissues were collected immediately after the cessation of the heart beat.The product of RT-PCR.DAZL1 expression was detected in all five samples.DAZL1 is not only expressed in human testes but also in ovaries. It may play a role in germ cell survival and gonad development in both sexes.

Related Organizations

Memorial Hospital of South Bend
United States
Chang Gung University
Taiwan
Kaohsiung Chang Gung Memorial Hospital
Taiwan

Keywords

Adult, Male, Reverse Transcriptase Polymerase Chain Reaction, Ovary, Gene Expression Regulation, Developmental, Proteins, RNA-Binding Proteins, Abortion, Induced, Oligospermia, Blotting, Southern, Endometrium, Humans, Female

12 Research products, page 1 of 2

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype
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