MPL W515L mutation in pediatric essential thrombocythemia
Copyright policy )MPL W515L mutation in pediatric essential thrombocythemia
AbstractEssential thrombocythemia (ET) is extremely rare in the pediatric population. In most patients no molecular abnormality can be found, with about 40% of pediatric patients harboring a JAK2 V617F mutation. Another recurrent mutation, involving a W to L or K transversion at MPL codon 515, has been reported in about 3–8% of adult ET patients. Herein we describe this mutation in a pediatric patient. Pediatr Blood Cancer 2013;60E52‐E54. © 2013 Wiley Periodicals, Inc.
- University of Padua Italy
Adult, Male, Amino Acid Substitution, Child, Preschool, Mutation, Missense, Humans, Janus Kinase 2, Receptors, Thrombopoietin, Thrombocythemia, Essential
Adult, Male, Amino Acid Substitution, Child, Preschool, Mutation, Missense, Humans, Janus Kinase 2, Receptors, Thrombopoietin, Thrombocythemia, Essential
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