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SnapShot: Mitochondrial Architecture

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2012 English Publisher:Elsevier BVJournal:Cell, volume 149, pages 722-7,220 (issn: 0092-8674, Copyright policy )
Authors: Neupert, W.;

doi: 10.1016/j.cell.2012.04.010

pmid: 22541440

handle: 11858/00-001M-0000-0010-5234-D

Abstract

1 TM domain; C-term in IMS and N-term in the matrix. IBM & CJ; self-oligomerizes, binds MICOS/MINOS/MitOS components and Sam50, Tob38, Ugo1, Fzo1.Yeast are viable but exhibit altered mtDNA inheritance and decreased respiratory growth. Mammals and worms exhibit increased ROS production and apoptosis.Loss of CJ, altered cristae structure, accumulation of cristae stacks and cristae rims. Higher membrane potential.Mos1 (Mcs10, Mio10, YC1057C-A)

Related Organizations
Keywords

Mitochondrial Proteins, Biochemistry, Genetics and Molecular Biology(all), Animals, Humans, Saccharomyces cerevisiae, Mitochondria

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    popularity
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
20
Top 10%
Top 10%
Top 10%
hybrid