Dynein Structure And Function
Copyright policy )Dynein Structure And Function
ABSTRACT The structure of dynein isolated from several sources follows the pattern first observed with Tetrahymena 22 S dynein, which has three globular heads attached by three flexible strands to a root-like base. Recent biochemical data indicate that there is one ATPase site on each dynein head and that all three heads interact with microtubules in an ATP-sensitive manner. Accordingly, images of dynein in situ can be interpreted in terms of a model for crossbridge action where the roots of the bouquet anchor the dynein to the A-tubule and all three heads reach out to interact with the B-tubule in an ATP-dependent reaction to produce a force for sliding.
- Pennsylvania State University United States
- Parker University United States
Adenosine Triphosphatases, Structure-Activity Relationship, Adenosine Triphosphate, Binding Sites, Animals, Dyneins, Microtubules, Models, Biological
Adenosine Triphosphatases, Structure-Activity Relationship, Adenosine Triphosphate, Binding Sites, Animals, Dyneins, Microtubules, Models, Biological
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).12 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!