Transcript elongation on a nucleoprotein template
Copyright policy )Transcript elongation on a nucleoprotein template
Chromatin forms a general, repeating barrier to elongation of transcripts by eukaryotic RNA polymerases. Recent studies of nucleosome structure and histone modifications reveal a set of likely mechanisms for control of elongation through chromatin. Genetic and biochemical studies of transcription have identified a set of accessory factors for transcript elongation by RNA polymerase II (Pol II) that appear to function in the context of chromatin. The C-terminal repeated domain (CTD) of Pol II may also play a role in regulating elongation through chromatin.
- University of California, Santa Cruz United States
Transcription, Genetic, Peptide Chain Elongation, Translational, Saccharomyces cerevisiae, Templates, Genetic, Chromatin, Nucleosomes, Nucleoproteins, Gene Expression Regulation, RNA Polymerase II, Transcription Factors, General, Transcriptional Elongation Factors, Peptide Chain Initiation, Translational
Transcription, Genetic, Peptide Chain Elongation, Translational, Saccharomyces cerevisiae, Templates, Genetic, Chromatin, Nucleosomes, Nucleoproteins, Gene Expression Regulation, RNA Polymerase II, Transcription Factors, General, Transcriptional Elongation Factors, Peptide Chain Initiation, Translational
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