Interaction between Arginase and Ornithine Carbamoyltransferase in Saccharomyces cerevisiae
pmid: 5116613
Interaction between Arginase and Ornithine Carbamoyltransferase in Saccharomyces cerevisiae
The inhibition of ornithine carbamoyltransferase by arginase in Saccharomyces cerevisiae, which is under the control of arginine and ornithine, involves a regulatory site on the ornithine carbamoyltransferase distinct from its catalytic site. This regulatory site is responsible for the partial inhibition of ornithine carbamoyltransferase by excess of ornithine. The strong inhibition of ornithine carbamoyltransferase by arginase in the presence of arginine requires the integrity of the mechanism which leads to partial inhibition by excess of ornithine.
- Université Libre de Bruxelles Belgium
Genetics, Microbial, Ornithine, Saccharomyces -- enzymology, Hot Temperature, Acylation, Arginine, Models, Biological, Saccharomyces, Microbial, Models, Genetics, Polyamines, Ornithine Carbamoyltransferase -- antagonists & inhibitors, Ornithine Carbamoyltransferase, Binding Sites, Arginase, Aminobutyrates, Imidazoles, Sciences bio-médicales et agricoles, Biological, Kinetics, Mutation, Carbamates, Aminobutyric Acids
Genetics, Microbial, Ornithine, Saccharomyces -- enzymology, Hot Temperature, Acylation, Arginine, Models, Biological, Saccharomyces, Microbial, Models, Genetics, Polyamines, Ornithine Carbamoyltransferase -- antagonists & inhibitors, Ornithine Carbamoyltransferase, Binding Sites, Arginase, Aminobutyrates, Imidazoles, Sciences bio-médicales et agricoles, Biological, Kinetics, Mutation, Carbamates, Aminobutyric Acids
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