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European Journal of Biochemistry
Article . 1971 . Peer-reviewed
License: Wiley Online Library User Agreement
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Interaction between Arginase and Ornithine Carbamoyltransferase in Saccharomyces cerevisiae

The Regulatory Site for Ornithine
Authors: Messenguy, Francine; Penninckx, Michel; Wiame, Jean-Marie;

Interaction between Arginase and Ornithine Carbamoyltransferase in Saccharomyces cerevisiae

Abstract

The inhibition of ornithine carbamoyltransferase by arginase in Saccharomyces cerevisiae, which is under the control of arginine and ornithine, involves a regulatory site on the ornithine carbamoyltransferase distinct from its catalytic site. This regulatory site is responsible for the partial inhibition of ornithine carbamoyltransferase by excess of ornithine. The strong inhibition of ornithine carbamoyltransferase by arginase in the presence of arginine requires the integrity of the mechanism which leads to partial inhibition by excess of ornithine.

Related Organizations
Keywords

Genetics, Microbial, Ornithine, Saccharomyces -- enzymology, Hot Temperature, Acylation, Arginine, Models, Biological, Saccharomyces, Microbial, Models, Genetics, Polyamines, Ornithine Carbamoyltransferase -- antagonists & inhibitors, Ornithine Carbamoyltransferase, Binding Sites, Arginase, Aminobutyrates, Imidazoles, Sciences bio-médicales et agricoles, Biological, Kinetics, Mutation, Carbamates, Aminobutyric Acids

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    93
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
93
Average
Top 1%
Top 10%
bronze