Corepressor Rcor1 is essential for murine erythropoiesis
Copyright policy )Corepressor Rcor1 is essential for murine erythropoiesis
Key PointsRcor1 knockout mice show a block in fetal erythropoiesis at the proerythroblast stage. Rcor1 represses expression of HSCs and myeloid genes during erythropoiesis, including Csf2rb, which is important in myeloid function.
- Vollum Institute United States
- Boston Children's Hospital United States
- Harvard Medical School United States
- Harvard University United States
- OREGON HEALTH &SCIENCE UNIVERSITY
Erythroid Precursor Cells, Mice, Knockout, Erythroblasts, Gene Expression Regulation, Developmental, Embryo, Mammalian, Receptors, Interleukin-3, Cytokine Receptor Common beta Subunit, Mice, Animals, Erythropoiesis, Myeloid Cells, Co-Repressor Proteins, Cells, Cultured, Gene Deletion, Signal Transduction
Erythroid Precursor Cells, Mice, Knockout, Erythroblasts, Gene Expression Regulation, Developmental, Embryo, Mammalian, Receptors, Interleukin-3, Cytokine Receptor Common beta Subunit, Mice, Animals, Erythropoiesis, Myeloid Cells, Co-Repressor Proteins, Cells, Cultured, Gene Deletion, Signal Transduction
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