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Fertility and Sterility
Article . 2006 . Peer-reviewed
License: Elsevier Non-Commercial
Data sources: Crossref
https://pubmed.ncbi.nlm.nih.go...
Article . 2006
Data sources: Europe PubMed Central
https://dx.doi.org/10.1016/j.f...
Article
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Characterization of estrogen receptors alpha and beta in uterine leiomyoma cells

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2006 English Publisher:Elsevier BVJournal:Fertility and Sterility, volume 86, pages 1,736-1,743 (issn: 0015-0282, Copyright policy )
Authors: Francisco, Valladares; Ignacio, Frías; Delia, Báez; Candelaria, García; Francisco J, López; James D, Fraser; Yurena, Rodríguez; +3 Authors

doi: 10.1016/j.fertnstert.2006.05.047

pmid: 17011556

Characterization of estrogen receptors alpha and beta in uterine leiomyoma cells

Abstract

Cellular and subcellular localization of estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta) in uterine leiomyomas.Retrospective study.University of La Laguna (ULL) and Canary University Hospital (HUC).Premenopausal and postmenopausal women with uterine leiomyomas.Hysterectomy and myomectomy.Estrogen receptor alpha was only present in smooth muscle cells with variation in the subcellular location in different leiomyomas. Estrogen receptor beta was widely distributed in smooth muscle, endothelial, and connective tissue cells with nuclear location in all cases studied; variations were only found in the muscle cells for this receptor.Estrogens operate in leiomyoma smooth muscle cells through different receptors, alpha and beta. However they only act through the ERbeta in endothelial and connective cells.

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Keywords

Adult, Aging, Leiomyoma, Myocytes, Smooth Muscle, Estrogen Receptor alpha, Middle Aged, Neoplasm Proteins, Uterine Neoplasms, Biomarkers, Tumor, Estrogen Receptor beta, Humans, Female, Tissue Distribution, Aged, Retrospective Studies

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    		 25
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    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
25
Average
Top 10%
Top 10%
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