Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
Copyright policy )Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratorysyndrome (SARS). The sequence of the complete genome of SARS-CoV was determined, and the initial characterization of the viral genome is presented in this report. The genome of SARS-CoV is 29,727 nucleotides in length and has 11 open reading frames, and its genome organization is similar to that of other coronaviruses. Phylogenetic analyses and sequence comparisons showed that SARS-CoV is not closelyrelated to anyof the previouslycharacterized coronaviruses.
- Centers for Disease Control and Prevention United States
- Bernhard Nocht Institute for Tropical Medicine Germany
- National Center for Emerging and Zoonotic Infectious Diseases United States
- Leibniz Association Germany
- University of California, San Francisco United States
DNA, Complementary, Membrane Glycoproteins, Coronavirus M Proteins, Molecular Sequence Data, Genome, Viral, Nucleocapsid Proteins, Regulatory Sequences, Nucleic Acid, RNA-Dependent RNA Polymerase, EMC MM-04-27-01, Coronavirus, Open Reading Frames, Severe acute respiratory syndrome-related coronavirus, Endopeptidases, Coronavirus Nucleocapsid Proteins, Humans, RNA, Viral, Amino Acid Sequence, RNA, Messenger, Conserved Sequence, Phylogeny, Polyproteins
DNA, Complementary, Membrane Glycoproteins, Coronavirus M Proteins, Molecular Sequence Data, Genome, Viral, Nucleocapsid Proteins, Regulatory Sequences, Nucleic Acid, RNA-Dependent RNA Polymerase, EMC MM-04-27-01, Coronavirus, Open Reading Frames, Severe acute respiratory syndrome-related coronavirus, Endopeptidases, Coronavirus Nucleocapsid Proteins, Humans, RNA, Viral, Amino Acid Sequence, RNA, Messenger, Conserved Sequence, Phylogeny, Polyproteins
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