Pyk2 regulates cell-edge protrusion dynamics by interacting with Crk
Pyk2 regulates cell-edge protrusion dynamics by interacting with Crk
A novel model is described by which Pyk2 regulates the dynamics of cell-edge protrusions via direct and indirect interactions with Crk, which enable fine-tuning of cell-edge protrusion dynamics and consequent cell motility on the one hand together with tight regulation of cell motility on the other hand.
- Tel Aviv University Israel
- Bar-Ilan University Israel
Articles, Fibroblasts, Proto-Oncogene Proteins c-crk, Mice, Focal Adhesion Kinase 2, Cell Movement, Animals, Cell Surface Extensions, Mitogen-Activated Protein Kinases, Phosphorylation, Cytoskeleton, Protein Binding, Signal Transduction
Articles, Fibroblasts, Proto-Oncogene Proteins c-crk, Mice, Focal Adhesion Kinase 2, Cell Movement, Animals, Cell Surface Extensions, Mitogen-Activated Protein Kinases, Phosphorylation, Cytoskeleton, Protein Binding, Signal Transduction
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