Choosing a cell fate: a view from the Notch locus
pmid: 1668193
Choosing a cell fate: a view from the Notch locus
During the development of Drosophila melanogaster, individual cells must make choices between a restricted set of possible fates in order to give rise to spatial patterns composed of different types of differentiated cells. The Notch locus appears to play a central and general role in the regulative events that control the local architecture of the final cellular pattern in several tissues, among them being the central and peripheral nervous systems.
- Yale University United States
- French Institute of Health and Medical Research France
- Howard Hughes Medical Institute United States
Receptors, Notch, Mosaicism, Embryonic Development, Membrane Proteins, Cell Differentiation, Epistasis, Genetic, Receptors, Cell Surface, Nervous System, Feedback, Embryonic and Fetal Development, Drosophila melanogaster, Gene Expression Regulation, Genes, Insect Hormones, Ectoderm, Animals, Drosophila Proteins
Receptors, Notch, Mosaicism, Embryonic Development, Membrane Proteins, Cell Differentiation, Epistasis, Genetic, Receptors, Cell Surface, Nervous System, Feedback, Embryonic and Fetal Development, Drosophila melanogaster, Gene Expression Regulation, Genes, Insect Hormones, Ectoderm, Animals, Drosophila Proteins
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