Additional file 16: Figure S6. of Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
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Haeussler, Maximilian; Schönig, Kai; Eckert, Hélène; Eschstruth, Alexis; Mianné, Joffrey; Jean-Baptiste Renaud; Schneider-Maunoury, Sylvie; +5 Authors
Haeussler, Maximilian; Schönig, Kai; Eckert, Hélène; Eschstruth, Alexis; Mianné, Joffrey; Jean-Baptiste Renaud; Schneider-Maunoury, Sylvie; Shkumatava, Alena; Teboul, Lydia; Kent, Jim; Jean-Stephane Joly; Concordet, Jean-Paul;
Additional file 16: Figure S6. of Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
Precision/recall curves for the large-scale datasets. The precision/recall plot for the Wong score on the Chari dataset looks different to that in the Wong et al. article as our study is analyzing only full datasets and Wong et al. used cross-fold data. The datasets by Hart, Doench 2016, Koike-Yusa, or Wang/Xu give the best impression of the Wong score on independent data that was not used for training by Wong et al. (PDF 87 kb)
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