Solving the centriole disengagement puzzle
Copyright policy ) Andrew M, Fry;
Solving the centriole disengagement puzzle
The microcephaly protein, Cep215, contributes to the engagement of duplicated centrioles in interphase. Now two distinct pools of Cep215 at centrosomes are identified, one bound to Cep68 and the other to pericentrin. Plk1-mediated degradation of Cep68 and separase-mediated cleavage of pericentrin release both pools of Cep215, thereby promoting centriole disengagement.
- University of Leicester United Kingdom
Proteolysis, Intracellular Signaling Peptides and Proteins, Humans, Cell Cycle Proteins, Nerve Tissue Proteins, Antigens, Microtubule-Associated Proteins, Centrioles
Proteolysis, Intracellular Signaling Peptides and Proteins, Humans, Cell Cycle Proteins, Nerve Tissue Proteins, Antigens, Microtubule-Associated Proteins, Centrioles
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citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 8
Average
Average
Average