Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjögren’s syndrome
Copyright policy )Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjögren’s syndrome
Key Points 77% of patients with primary Sjögren’s syndrome and mucosa-associated lymphoid tissue lymphoma have functional abnormalities of A20. A20 inactivation plays a key role in lymphomagenesis in the context of autoimmunity.
- Inserm France
- Institut de Biologie François-JACOB France
- University of California San Francisco Medical Center United States
- Hôpitaux universitaires Paris Sud France
- Université de Bretagne Occidentale France
MESH: Neoplasm Proteins, Male, [SDV]Life Sciences [q-bio], MESH: NF-kappa B, 610, Marginal Zone, Polymorphism, Single Nucleotide, MESH: Intracellular Signaling Peptides and Proteins, MESH: Germ-Line Mutation, 616, Humans, Prospective Studies, MESH: Polymorphism, Germ-Line Mutation, Tumor Necrosis Factor alpha-Induced Protein 3, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, MESH: Humans, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, B-Cell, Intracellular Signaling Peptides and Proteins, NF-kappa B, Nuclear Proteins, Single Nucleotide, MESH: Follow-Up Studies, Exons, Lymphoma, B-Cell, Marginal Zone, MESH: Prospective Studies, MESH: Male, Neoplasm Proteins, [SDV] Life Sciences [q-bio], DNA-Binding Proteins, MESH: Sjogren's Syndrome, Sjogren's Syndrome, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Female, MESH: Tumor Necrosis Factor alpha-Induced Protein 3, MESH: Exons, MESH: Lymphoma, MESH: Nuclear Proteins, MESH: Female, MESH: DNA-Binding Proteins, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Follow-Up Studies
MESH: Neoplasm Proteins, Male, [SDV]Life Sciences [q-bio], MESH: NF-kappa B, 610, Marginal Zone, Polymorphism, Single Nucleotide, MESH: Intracellular Signaling Peptides and Proteins, MESH: Germ-Line Mutation, 616, Humans, Prospective Studies, MESH: Polymorphism, Germ-Line Mutation, Tumor Necrosis Factor alpha-Induced Protein 3, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, MESH: Humans, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, B-Cell, Intracellular Signaling Peptides and Proteins, NF-kappa B, Nuclear Proteins, Single Nucleotide, MESH: Follow-Up Studies, Exons, Lymphoma, B-Cell, Marginal Zone, MESH: Prospective Studies, MESH: Male, Neoplasm Proteins, [SDV] Life Sciences [q-bio], DNA-Binding Proteins, MESH: Sjogren's Syndrome, Sjogren's Syndrome, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Female, MESH: Tumor Necrosis Factor alpha-Induced Protein 3, MESH: Exons, MESH: Lymphoma, MESH: Nuclear Proteins, MESH: Female, MESH: DNA-Binding Proteins, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Follow-Up Studies
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