Field effect

Name: Field effect
Creator: Sarah Seton-Rogers
Keywords: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Article 05 Jul 2012 English Publisher:Springer Science and Business Media LLCJournal:Nature Reviews Cancer, volume 12, pages 508-509 (issn: 1474-175X, eissn: 1474-1768,

Authors: Sarah Seton-Rogers;

doi: 10.1038/nrc3324

pmid: 22763663

Field effect

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Abstract

Knockout of the Notch effector Rbpjk in mesenchymal fibroblasts enhances the formation of squamous cell carcinomas of the skin in mice, and similar changes can be induced by exposure of human skin to ultraviolet A irradiation.

9 Research products, page 1 of 1

Abstract IA10: Convergent control of cancer associated fibroblast activation and field cancerization by Notch/CSL and p53 signaling
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Smooth Muscle α-Actin Is a Direct Target of Notch/CSL
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Global changes in gene expression in dermal fibroblasts with in vivo and in vitro deletion of the RBP-Jk gene
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PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation
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Collaboration Between RUNX and NOTCH Pathways in T-Cell Acute Lymphoblastic Leukemia
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Global changes in gene expression in dermal fibroblasts with in vivo and in vitro deletion of the RBP-Jk gene
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Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer
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Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis
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Multifocal Epithelial Tumors and Field Cancerization from Loss of Mesenchymal CSL Signaling
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