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The JAK/STAT pathway and Drosophila development

doi: 10.1002/bies.10016
pmid: 11746233
The JAK/STAT pathway and Drosophila development
AbstractThe JAK/STAT signal transduction pathway plays a critical role in mammalian cells, particularly in hematopoiesis and immune responses. Several components of this pathway have been identified and characterized in Drosophila. Mutational analyses of these components have revealed a number of interesting developmental roles, and provide a mechanism to identify other interacting molecules and pathways. Hence, the JAK/STAT pathway in Drosophila serves as an attractive model for in vivo functional analyses of JAK/STAT signaling. BioEssays 23:1138–1147, 2001. © 2001 John Wiley & Sons, Inc.
- Harvard University United States
- Massachusetts General Hospital United States
- Cardiovascular Institute Hospital Japan
- The University of Texas System United States
- The University of Texas Health Science Center at Houston United States
Extremities, Protein-Tyrosine Kinases, Sex Determination Processes, Eye, DNA-Binding Proteins, STAT Transcription Factors, Trans-Activators, Animals, Drosophila Proteins, Insect Proteins, Wings, Animal, Drosophila, Glycoproteins, Janus Kinases, Signal Transduction, Transcription Factors
Extremities, Protein-Tyrosine Kinases, Sex Determination Processes, Eye, DNA-Binding Proteins, STAT Transcription Factors, Trans-Activators, Animals, Drosophila Proteins, Insect Proteins, Wings, Animal, Drosophila, Glycoproteins, Janus Kinases, Signal Transduction, Transcription Factors
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