Association of hyperphosphorylated paratarg-7, the first autosomal-dominantly inherited risk factor for hematological neoplasms, with MGUS and multiple myeloma in different ethnic groups.

descriptionPublicationkeyboard_double_arrow_right Article 20 May 2010 English Publisher:American Society of Clinical Oncology (ASCO)Journal:Journal of Clinical Oncology, volume 28, pages 8,111-8,111 (issn: 0732-183X, eissn: 1527-7755,

Authors: S. Grass; S. Iida; A. Wikowicz; N. Fadle; A. Inagaki; K. Preuss; M. Ziepert; +2 Authors

doi: 10.1200/jco.2010.28.15_suppl.8111

Association of hyperphosphorylated paratarg-7, the first autosomal-dominantly inherited risk factor for hematological neoplasms, with MGUS and multiple myeloma in different ethnic groups.

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Abstract

8111 Background: Hyperphosphorylated paratarg-7 (pP-7) is a frequent target of paraproteins in Caucasian patients with MGUS/MM (Preuss et al. Int J Cancer. 2009; 125:656-61). Carriers of pP-7 have ...

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Abstract 1169: Paratarg-7, the first autosomal-dominantly inherited risk factor for hematological malignancies: single nucelotide poylmorphism- and microsatellite-based genome-wide linkage analysis
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Association of a dominantly inherited hyperphosphorylated paraprotein target with sporadic and familial multiple myeloma and monoclonal gammopathy of undetermined significance: a case–control study
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Hyperphosphorylation of autoantigenic targets of paraproteins is due to inactivation of PP2A
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A frequent target of paraproteins in the sera of patients with multiple myeloma and MGUS
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Abstract 4772: Hyperphosphorylated Paratarg-7, the first autosomal-dominantly inherited risk factor for hematological neoplasias: hyperphosphorylation by PKCzeta
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Hyperphosphorylated Paratarg-7 Is a Frequent Antigenic Target of IgM Paraproteins, Is Dominantly Inherited and Represents a Highly Significant Risk Factor for Monoclonal Gammopathy of Undetermined Significance of the IgM Type (IgM-MGUS) and Waldenstrom's Macroglobulinemia (WM), Allowing for the Identification of Family Members at Risk in Cases of Familial IgM-MGUS and WM.
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Over one‐third of African‐American MGUS and multiple myeloma patients are carriers of hyperphosphorylated paratarg‐7, an autosomal dominantly inherited risk factor for MGUS/MM
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Hyperphosphorylation of Antigenic Targets of Paraproteins In MGUS and Multiple Myeloma (MM) Is a Consistent Finding: Implications for the Pathogenesis of MGUS/MM
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Hyperphosphorylated paratarg-7: a new molecularly defined risk factor for monoclonal gammopathy of undetermined significance of the IgM type and Waldenström macroglobulinemia
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