Cutaneous Neoplasms Showing EWSR1 Rearrangement
Copyright policy )Cutaneous Neoplasms Showing EWSR1 Rearrangement
Rearrangements of the EWSR1 gene are found in an increasing number of human neoplasms, including several tumors that can involve the skin: Ewing sarcoma/primitive neuroectodermal tumor, angiomatoid (malignant) fibrous histiocytoma, myoepithelioma of soft tissue, and clear cell sarcoma. Although these tumors share this common genetic link, they have very different clinical features, morphology, immunophenotype, and sometimes fusion gene partners; these will be the subjects of this review.
- Mayo Clinic United States
- Mayo Clinic United States
Gene Rearrangement, Skin Neoplasms, Oncogene Proteins, Fusion, RNA-Binding Proteins, Soft Tissue Neoplasms, Histiocytoma, Malignant Fibrous, Sarcoma, Ewing, Myoepithelioma, Gene Expression Regulation, Neoplastic, Humans, Neuroectodermal Tumors, Primitive, Calmodulin-Binding Proteins, Sarcoma, Clear Cell, Gene Fusion, RNA-Binding Protein EWS, In Situ Hybridization, Fluorescence
Gene Rearrangement, Skin Neoplasms, Oncogene Proteins, Fusion, RNA-Binding Proteins, Soft Tissue Neoplasms, Histiocytoma, Malignant Fibrous, Sarcoma, Ewing, Myoepithelioma, Gene Expression Regulation, Neoplastic, Humans, Neuroectodermal Tumors, Primitive, Calmodulin-Binding Proteins, Sarcoma, Clear Cell, Gene Fusion, RNA-Binding Protein EWS, In Situ Hybridization, Fluorescence
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