No association of DAPK1 and ABCA2 SNPs on chromosome 9 with Alzheimer's disease
Copyright policy )No association of DAPK1 and ABCA2 SNPs on chromosome 9 with Alzheimer's disease
Recently genetic variation in the DAPK1 and ABCA2 genes has been reported to be associated with late- and early-onset Alzheimer's disease (AD), respectively. We examined the most significant two single-nucleotide polymorphisms (SNPs) in DAPK1 in a large case-control cohort of late-onset subjects and matched controls and one of the most significant SNPs in ABCA2 in a small set of early-onset subjects as well. We did not detect associations with AD for any variation.
- University of Pittsburgh United States
Genotype, Autophagy-Related Proteins, Cell Cycle Proteins, Polymorphism, Single Nucleotide, Cohort Studies, Death-Associated Protein Kinases, Gene Frequency, Alzheimer Disease, Case-Control Studies, Calcium-Calmodulin-Dependent Protein Kinases, Humans, ATP-Binding Cassette Transporters, Apoptosis Regulatory Proteins, Carrier Proteins, Chromosomes, Human, Pair 9, Adaptor Proteins, Signal Transducing
Genotype, Autophagy-Related Proteins, Cell Cycle Proteins, Polymorphism, Single Nucleotide, Cohort Studies, Death-Associated Protein Kinases, Gene Frequency, Alzheimer Disease, Case-Control Studies, Calcium-Calmodulin-Dependent Protein Kinases, Humans, ATP-Binding Cassette Transporters, Apoptosis Regulatory Proteins, Carrier Proteins, Chromosomes, Human, Pair 9, Adaptor Proteins, Signal Transducing
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