Human leukocyte antigen-G polymorphism in relation to expression, function, and disease
pmid: 19651180
Human leukocyte antigen-G polymorphism in relation to expression, function, and disease
Human leukocyte antigen-G (HLA-G) is a nonclassical class Ib molecule belonging to the major histocompatibility complex. HLA-G appears to play a role in the suppression of immune responses and contribute to long-term immune escape or tolerance. The focus of this review is polymorphism in the HLA-G gene and protein and its possible importance in expression, function, and disease associations.
- Roskilde University Denmark
- University of Copenhagen Denmark
- University of Copenhagen Denmark
HLA-G Antigens, Polymorphism, Genetic, Histocompatibility Antigens Class I, Exons, Organ Transplantation, Regulatory Sequences, Nucleic Acid, Asthma, Linkage Disequilibrium, Autoimmune Diseases, Pregnancy Complications, HLA Antigens, Pregnancy, Humans, Disease, Female, 3' Untranslated Regions, Alleles
HLA-G Antigens, Polymorphism, Genetic, Histocompatibility Antigens Class I, Exons, Organ Transplantation, Regulatory Sequences, Nucleic Acid, Asthma, Linkage Disequilibrium, Autoimmune Diseases, Pregnancy Complications, HLA Antigens, Pregnancy, Humans, Disease, Female, 3' Untranslated Regions, Alleles
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