Transcription regulation and animal diversity
doi: 10.1038/nature01763
pmid: 12853946
Transcription regulation and animal diversity
Whole-genome sequence assemblies are now available for seven different animals, including nematode worms, mice and humans. Comparative genome analyses reveal a surprising constancy in genetic content: vertebrate genomes have only about twice the number of genes that invertebrate genomes have, and the increase is primarily due to the duplication of existing genes rather than the invention of new ones. How, then, has evolutionary diversity arisen? Emerging evidence suggests that organismal complexity arises from progressively more elaborate regulation of gene expression.
- University of California, Berkeley United States
Gene Expression Regulation, Transcription, Genetic, Animals, Humans, DNA, Regulatory Sequences, Nucleic Acid, Chromatin, Ecosystem, Transcription Factors
Gene Expression Regulation, Transcription, Genetic, Animals, Humans, DNA, Regulatory Sequences, Nucleic Acid, Chromatin, Ecosystem, Transcription Factors
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