The E3 ubiquitin ligase UBR5 is recurrently mutated in mantle cell lymphoma
pmid: 23407552
The E3 ubiquitin ligase UBR5 is recurrently mutated in mantle cell lymphoma
Key Points UBR5 is recurrently mutated in mantle cell lymphoma with a C-terminal cluster of deleterious mutations.
- Canada's Michael Smith Genome Sciences Centre Canada
- University of British Columbia Canada
- BC Cancer Agency Canada
Base Sequence, Tumor Suppressor Proteins, Ubiquitin-Protein Ligases, Molecular Sequence Data, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Lymphoma, Mantle-Cell, Protein Serine-Threonine Kinases, Cohort Studies, DNA-Binding Proteins, Cell Line, Tumor, Mutation, Humans, Cyclin D1, Amino Acid Sequence, Receptor, Notch1, Tumor Suppressor Protein p53, Sequence Alignment, Sequence Deletion
Base Sequence, Tumor Suppressor Proteins, Ubiquitin-Protein Ligases, Molecular Sequence Data, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Lymphoma, Mantle-Cell, Protein Serine-Threonine Kinases, Cohort Studies, DNA-Binding Proteins, Cell Line, Tumor, Mutation, Humans, Cyclin D1, Amino Acid Sequence, Receptor, Notch1, Tumor Suppressor Protein p53, Sequence Alignment, Sequence Deletion
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