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Fertility and Sterility
Article . 2008 . Peer-reviewed
License: Elsevier Non-Commercial
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Hal
Article . 2008
Data sources: Hal
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Testicular and epididymal dual origin of hCAP-18/SOB3, a human sperm protein

Authors: Doussau, Mireille; Lasserre, Andrea; Hammami-Hamza, Sonia; Massaad, C.; Gasc, Jean Marie; Finaz, Catherine;

Testicular and epididymal dual origin of hCAP-18/SOB3, a human sperm protein

Abstract

The expression and localization of the human sperm protein hCAP-18/SOB3 were evaluated in human testis and epididymis through in situ hybridization and immunohistochemistry with the use of an anti-recombinant hCAP-18/SOB3 polyclonal antibody. Both hCAP-18/SOB3 messenger RNA and hCAP-18/SOB3 protein were detected in testis germinal cells (from late spermatogonia to spermatozoa) and in the epididymal epithelium. This localization is in agreement with the antimicrobial properties previously described and supports its involvement in zona pellucida binding, as we had previously suggested.

Keywords

Epididymis, Male, Cathelicidins, Testis, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Humans, Tissue Distribution, Spermatozoa, Antimicrobial Cationic Peptides

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    4
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
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Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average