Salvihispin A and its glycoside, two neo -clerodane diterpenoids with neurotrophic activities from Salvia hispanica L.
Authors: Min Fan; Yu Zhu; Zhi-Jun Zhang; Ru-Nan Du; Qin-Feng Zhu; Xing-De Wu; Qin-Shi Zhao;
Salvihispin A and its glycoside, two neo -clerodane diterpenoids with neurotrophic activities from Salvia hispanica L.
Abstract
A neo-clerodane diterpenoid, salvihispin A (1), as well as its glycoside, salvihispin A-2-O-beta-D-3-keto-glucopyranoside (2) were isolated from the aerial parts of Salvia hispanica. Compound 2 possessed an unusual 3-keto-glucopyranoside moiety. Their structures and absolute configurations were elucidated by extensive spectroscopic methods and confirmed by single crystal X-ray diffraction. Salvihispin A (1) and its glycoside (2) enhanced the neurite outgrowth of NGF-mediated PC12 cells at a concentration of 10 mu M. (C) 2017 Elsevier Ltd. All rights reserved.
Related Organizations
- Chinese Academy of Sciences China (People's Republic of)
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citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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