Cancer Cell
Article . 2015
License: Elsevier Non-Commercial
Data sources: BASE (Open Access Aggregator)
Functionally Relevant RNA Helicase Mutations in Familial and Sporadic Myeloid Malignancies
Authors: Antony-Debré, Iléana; Steidl, Ulrich;
pmid: 25965566
Functionally Relevant RNA Helicase Mutations in Familial and Sporadic Myeloid Malignancies
Abstract
In this issue of Cancer Cell, Polprasert and colleagues identified recurrent mutations in the DEAD/H-box RNA helicase gene DDX41 in familial and acquired cases of myelodsyplasia and acute myeloid leukemia. These mutations induce defects in RNA splicing and represent a new class of mutations in myeloid malignancies.
Related Organizations
- Albert Einstein College of Medicine United States
- Montefiore Medical Center United States
Keywords
Male, Cancer Research, Cell Biology, DEAD-box RNA Helicases, Leukemia, Myeloid, Acute, Oncology, Animals, Humans, Female, Germ-Line Mutation
Male, Cancer Research, Cell Biology, DEAD-box RNA Helicases, Leukemia, Myeloid, Acute, Oncology, Animals, Humans, Female, Germ-Line Mutation
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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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