A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells
A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells
The ATP-releasing channel Panx1 is specifically involved in blood pressure regulation by adrenergic signaling.
- University of Calgary Canada
- University of Virginia United States
- Hotchkiss Brain Institute Canada
Analysis of Variance, Serotonin, Patch-Clamp Techniques, Endothelin-1, Blotting, Western, Molecular Sequence Data, Fluorescent Antibody Technique, Blood Pressure, Nerve Tissue Proteins, Connexins, Muscle, Smooth, Vascular, Mice, Inbred C57BL, Mice, Adenosine Triphosphate, HEK293 Cells, Receptors, Adrenergic, alpha-1, Mutagenesis, Site-Directed, Animals, Humans, Amino Acid Sequence
Analysis of Variance, Serotonin, Patch-Clamp Techniques, Endothelin-1, Blotting, Western, Molecular Sequence Data, Fluorescent Antibody Technique, Blood Pressure, Nerve Tissue Proteins, Connexins, Muscle, Smooth, Vascular, Mice, Inbred C57BL, Mice, Adenosine Triphosphate, HEK293 Cells, Receptors, Adrenergic, alpha-1, Mutagenesis, Site-Directed, Animals, Humans, Amino Acid Sequence
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