Building a Kinetic Model of Trehalose Biosynthesis in Saccharomyces cerevisiae
Building a Kinetic Model of Trehalose Biosynthesis in Saccharomyces cerevisiae
In this chapter, we describe the steps needed to create a kinetic model of a metabolic pathway based on kinetic data from experimental measurements and literature review. Our methodology is presented by utilizing the example of trehalose metabolism in yeast. The biology of the trehalose cycle is briefly reviewed and discussed.
- University of Salford United Kingdom
- University of Luxembourg Luxembourg
UTP-Glucose-1-Phosphate Uridylyltransferase/chemistry/physiology, Saccharomyces cerevisiae Proteins, UTP-Glucose-1-Phosphate Uridylyltransferase, Physiological, Saccharomyces cerevisiae/enzymology/metabolism/physiology, Saccharomyces cerevisiae Proteins/chemistry/physiology, : Multidisciplinary, general & others [F99] [Life sciences], Saccharomyces cerevisiae, Stress, Models, Biological, : Multidisciplinaire, généralités & autres [F99] [Sciences du vivant], Glucosyltransferases/chemistry, Models, Stress, Physiological, Gene Expression Regulation, Fungal, Computer Simulation, Glucosyltransferases/chemistry/physiology, Phosphoglucomutase/chemistry/physiology, Glucose-6-Phosphate Isomerase/chemistry/physiology, Trehalose/biosynthesis, Enzyme Assays, Systems Biology, UTP-Glucose-1-Phosphate Uridylyltransferase/chemistry, Glucose-6-Phosphate Isomerase, Trehalose, Biological, Kinetics, Fungal, Gene Expression Regulation, Phosphoglucomutase, Glucosyltransferases, Saccharomyces cerevisiae Proteins/chemistry, Phosphoglucomutase/chemistry, Glucose-6-Phosphate Isomerase/chemistry, Glycolysis, Saccharomyces cerevisiae/enzymology, Algorithms, Metabolic Networks and Pathways
UTP-Glucose-1-Phosphate Uridylyltransferase/chemistry/physiology, Saccharomyces cerevisiae Proteins, UTP-Glucose-1-Phosphate Uridylyltransferase, Physiological, Saccharomyces cerevisiae/enzymology/metabolism/physiology, Saccharomyces cerevisiae Proteins/chemistry/physiology, : Multidisciplinary, general & others [F99] [Life sciences], Saccharomyces cerevisiae, Stress, Models, Biological, : Multidisciplinaire, généralités & autres [F99] [Sciences du vivant], Glucosyltransferases/chemistry, Models, Stress, Physiological, Gene Expression Regulation, Fungal, Computer Simulation, Glucosyltransferases/chemistry/physiology, Phosphoglucomutase/chemistry/physiology, Glucose-6-Phosphate Isomerase/chemistry/physiology, Trehalose/biosynthesis, Enzyme Assays, Systems Biology, UTP-Glucose-1-Phosphate Uridylyltransferase/chemistry, Glucose-6-Phosphate Isomerase, Trehalose, Biological, Kinetics, Fungal, Gene Expression Regulation, Phosphoglucomutase, Glucosyltransferases, Saccharomyces cerevisiae Proteins/chemistry, Phosphoglucomutase/chemistry, Glucose-6-Phosphate Isomerase/chemistry, Glycolysis, Saccharomyces cerevisiae/enzymology, Algorithms, Metabolic Networks and Pathways
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