Transposable elements controlling genetic instabilities in mammals
pmid: 6279728
Transposable elements controlling genetic instabilities in mammals
It is proposed that the instabilities in gene action of some alleles at certain loci in the mouse (e.g., a, c, H-2 Mi, p, pe, T, Va, W), which do not seem to conform to traditional hypotheses of gene action, are better interpretable in the light of modern studies of transposable DNA elements (insertion sequences and transposons of prokaryotic organisms; controlling elements of maize; transposable controlling elements of Drosophila). Some phenotypic evidence in the mouse in support of this hypothesis is presented for the a, Mi, p, and W loci, which affect pigmentation.
- University of Arkansas System United States
- Yale University United States
- University of Arkansas at Fayetteville United States
Pigmentation, Genetic Variation, Zea mays, Mice, Inbred C57BL, Mice, Dogs, Phenotype, DNA Transposable Elements, Animals, Humans, Drosophila
Pigmentation, Genetic Variation, Zea mays, Mice, Inbred C57BL, Mice, Dogs, Phenotype, DNA Transposable Elements, Animals, Humans, Drosophila
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