ASXL genes and RUNX1: an intimate connection?
Authors: Klaus H. Metzeler;
ASXL genes and RUNX1: an intimate connection?
Abstract
In this issue of Blood , Micol et al report the discovery of mutations in the additional sex combs-like 2 ( ASXL2 ) gene in about one-quarter of acute myeloid leukemia (AML) patients carrying the t(8;21) translocation.[1][1] ![Figure][2] ASXL gene mutations in t(8;21) AML. (A) ASXL2 is the
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Keywords
Male, Repressor Proteins, Leukemia, Myeloid, Acute, RUNX1 Translocation Partner 1 Protein, Oncogene Proteins, Fusion, Core Binding Factor Alpha 2 Subunit, Mutation, Humans, Female
Male, Repressor Proteins, Leukemia, Myeloid, Acute, RUNX1 Translocation Partner 1 Protein, Oncogene Proteins, Fusion, Core Binding Factor Alpha 2 Subunit, Mutation, Humans, Female
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