Identification of the MICA∗070 allele by sequencing and phasing
Copyright policy )Identification of the MICA∗070 allele by sequencing and phasing
A novel MICA allele, MICA*070, was defined by sequencing. The new allele differs from the MICA*008:04 sequence in exon 2, encoding a C instead of G corresponding to cDNA nucleotide position 183. This nucleotide substitution is predicted to encode serine instead of arginine at residue 38 of the α1 domain of the MICA molecule.
- Fujita Health University Japan
- Fred Hutchinson Cancer Research Center United States
- Fred Hutchinson Cancer Research Center South Africa
Polymorphism, Genetic, Base Sequence, Histocompatibility Antigens Class I, Molecular Sequence Data, Reproducibility of Results, Exons, Sequence Analysis, DNA, Polymerase Chain Reaction, Sequence Homology, Nucleic Acid, Humans, Alleles
Polymorphism, Genetic, Base Sequence, Histocompatibility Antigens Class I, Molecular Sequence Data, Reproducibility of Results, Exons, Sequence Analysis, DNA, Polymerase Chain Reaction, Sequence Homology, Nucleic Acid, Humans, Alleles
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