TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy

descriptionPublicationkeyboard_double_arrow_right Article 26 Nov 2021 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Immunology, volume 6 (eissn: 2470-9468,

Authors: Ferhat Ay; Haruka Miki; Donald T. Gracias; Rinkesh K. Gupta; Michael Croft; Michael Croft; Daniela Salgado Figueroa; +3 Authors

doi: 10.1126/sciimmunol.abi8823

pmid: 34797693

pmc: PMC8756771

TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy

- Summary
- Subjects
- Related research
  (12)
- Metrics

tips_and_updates
Recommended

Abstract

TWEAK synergizes with TNF and IL-17 in keratinocytes to drive psoriasis-like skin inflammation.

Related Organizations

University of California, San Diego
United States
La Jolla Institute For Allergy & Immunology
United States
Biogen (United States)
United States
University of California, San Diego
United States

Keywords

Keratinocytes, Male, Mice, Knockout, Interleukin-17, Cytokine TWEAK, Mice, Inbred C57BL, Disease Models, Animal, Mice, Tumor Necrosis Factors, Animals, Psoriasis

12 Research products, page 1 of 2

Uncharacterized protein
2017IsRelatedTo
Interleukin-17A
2017IsRelatedTo
Transcriptomic Analysis of Human Epidermal Keratinocytes Stimulated with TWEAK, TNF and IL-17A
2022IsRelatedTo
Uncharacterized protein
2017IsRelatedTo
Uncharacterized protein
2017IsRelatedTo
Tumor necrosis factor, isoform CRA_b
2017IsRelatedTo
Tumor necrosis factor alpha
2017IsRelatedTo
Tumor necrosis factor alpha
2017IsRelatedTo
Sequence Read Archive(SRA)
2022IsRelatedTo
Interleukin 17A
2017IsRelatedTo

chevron_left
1
2
chevron_right

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	68
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 1%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%