Interdomain Flexibility of Chikungunya Virus nsP2 Helicase-Protease Differentially Influences Viral RNA Replication and Infectivity
Copyright policy )WT| Genetic approaches to reducing vector competence of Aedes aegypti for chikungunya virus ,
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Yee-Song Law; Sainan Wang; Yaw Bia Tan; Orion Shih; Age Utt; Wei Yang Goh; Bing-Jun Lian; +4 Authors
Yee-Song Law; Sainan Wang; Yaw Bia Tan; Orion Shih; Age Utt; Wei Yang Goh; Bing-Jun Lian; Ming Wei Chen; U-Ser Jeng; Andres Merits; Dahai Luo;
Interdomain Flexibility of Chikungunya Virus nsP2 Helicase-Protease Differentially Influences Viral RNA Replication and Infectivity
CHIKV nsP2 plays multiple roles in viral RNA replication and virus-host interactions. The helicase and protease regions of nsP2 are connected through a short linker.
Singapore, Estonia
- Nanyang Technological University Singapore
- Univerity Tartu Estonia
- National Synchrotron Radiation Research Center Taiwan
- University of Tartu Estonia
- National Tsing Hua University Taiwan
:Biological sciences [Science], Alphavirus, Virus Replication, Cell Line, Protein Structure, Tertiary, Cysteine Endopeptidases, Mutation, Animals, Humans, RNA, Viral, Viral Replicase Complex Proteins, Amino Acid Sequence, Nonstructural Protein 2, Chikungunya virus, RNA Helicases
:Biological sciences [Science], Alphavirus, Virus Replication, Cell Line, Protein Structure, Tertiary, Cysteine Endopeptidases, Mutation, Animals, Humans, RNA, Viral, Viral Replicase Complex Proteins, Amino Acid Sequence, Nonstructural Protein 2, Chikungunya virus, RNA Helicases
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).23 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 23
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