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Nature Genetics
Article . 2002 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
Nature Genetics
Article . 2002
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Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

Authors: Eric C, Lai;

Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

Abstract

Micro RNAs are a large family of noncoding RNAs of 21-22 nucleotides whose functions are generally unknown. Here a large subset of Drosophila micro RNAs is shown to be perfectly complementary to several classes of sequence motif previously demonstrated to mediate negative post-transcriptional regulation. These findings suggest a more general role for micro RNAs in gene regulation through the formation of RNA duplexes.

Related Organizations
Keywords

RNA, Untranslated, Base Sequence, Sequence Homology, Amino Acid, Amino Acid Motifs, Molecular Sequence Data, Nucleic Acid Hybridization, MicroRNAs, Animals, Drosophila, RNA, Antisense, 5' Untranslated Regions, Caenorhabditis elegans, 3' Untranslated Regions

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1K
Top 0.1%
Top 0.1%
Top 0.1%