Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation
doi: 10.1038/ng865
pmid: 11896390
Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation
Micro RNAs are a large family of noncoding RNAs of 21-22 nucleotides whose functions are generally unknown. Here a large subset of Drosophila micro RNAs is shown to be perfectly complementary to several classes of sequence motif previously demonstrated to mediate negative post-transcriptional regulation. These findings suggest a more general role for micro RNAs in gene regulation through the formation of RNA duplexes.
- University of California, Berkeley United States
RNA, Untranslated, Base Sequence, Sequence Homology, Amino Acid, Amino Acid Motifs, Molecular Sequence Data, Nucleic Acid Hybridization, MicroRNAs, Animals, Drosophila, RNA, Antisense, 5' Untranslated Regions, Caenorhabditis elegans, 3' Untranslated Regions
RNA, Untranslated, Base Sequence, Sequence Homology, Amino Acid, Amino Acid Motifs, Molecular Sequence Data, Nucleic Acid Hybridization, MicroRNAs, Animals, Drosophila, RNA, Antisense, 5' Untranslated Regions, Caenorhabditis elegans, 3' Untranslated Regions
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