SLCO1B1,SLCO2B1, andSLCO1B3Polymorphisms and Susceptibility to Bladder Cancer Risk
Copyright policy )SLCO1B1,SLCO2B1, andSLCO1B3Polymorphisms and Susceptibility to Bladder Cancer Risk
A variety of carcinogens are excreted in urine and may be actively transported by organic anion-transporting polypeptides that encoded by SLCOs. In this study, we evaluated whether single nucleotide polymorphisms (SNPs) in SLCO1B1, SLCO2B1, and SLCO1B3 are associated with bladder cancer susceptibility. Our results, for the first time, indicated that polymorphisms of SLCO1B1 rs2306283 might be associated with bladder cancer risk. Therefore, SNPs in SLCO1B1 may be potential biomarkers for assessing the risk of bladder cancer.
Aged, 80 and over, Male, Liver-Specific Organic Anion Transporter 1, Organic Anion Transporters, Middle Aged, Organic Anion Transporters, Sodium-Independent, Polymorphism, Single Nucleotide, Solute Carrier Organic Anion Transporter Family Member 1B3, Urinary Bladder Neoplasms, Risk Factors, Humans, Female, Genetic Predisposition to Disease, Genetic Association Studies, Aged
Aged, 80 and over, Male, Liver-Specific Organic Anion Transporter 1, Organic Anion Transporters, Middle Aged, Organic Anion Transporters, Sodium-Independent, Polymorphism, Single Nucleotide, Solute Carrier Organic Anion Transporter Family Member 1B3, Urinary Bladder Neoplasms, Risk Factors, Humans, Female, Genetic Predisposition to Disease, Genetic Association Studies, Aged
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