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Journal of Innate Immunity
Article . 2010 . Peer-reviewed
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Journal of Innate Immunity
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Journal of Innate Immunity
Article . 2011
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https://dx.doi.org/10.1159/000...
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Clotting Factors and Eicosanoids Protect against Nematode Infections

descriptionPublicationkeyboard_double_arrow_right Article 16 Oct 2010 English Publisher:S. Karger AGJournal:Journal of Innate Immunity, volume 3, pages 65-70 (issn: 1662-811X, eissn: 1662-8128, Copyright policy )
Authors: Pavel, Hyrsl; Pavel, Dobes; Zhi, Wang; Thomas, Hauling; Christine, Wilhelmsson; Ulrich, Theopold;

doi: 10.1159/000320634

pmid: 20948189

Clotting Factors and Eicosanoids Protect against Nematode Infections

Abstract

We show that hemolymph clotting protects <i>Drosophila melanogaster</i> against infections with an entomopathogenic nematode and its symbiotic bacterium. We also provide biochemical and genetic evidence for an involvement of eicosanoids in the same infection model. Taken together, our results confirm the conserved nature of the immune function of clot formation.

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Keywords

Transglutaminases, Blood Coagulation Factors, Immunity, Innate, Rhabditida, Drosophila melanogaster, Hemolymph, Animals, Eicosanoids, Photorhabdus, Symbiosis, Blood Coagulation

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 63
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
63
Top 10%
Top 10%
Top 10%
gold
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