High-fat diet, obesity and prostate disease: the ATX–LPA axis?
Copyright policy )High-fat diet, obesity and prostate disease: the ATX–LPA axis?
The incidence of obesity, a potential risk factor for prostate disease, is rising sharply in the western world, as is the incidence of prostate tumors. In this extended Viewpoint, Kulkarni and Getzenberg propose that the relationship between obesity and prostate disease might be mediated by the autotaxin–lysophosphatidic acid (ATX–LPA) axis.
- Johns Hopkins Medicine United States
- Johns Hopkins University School of Medicine United States
Male, Prostatic Diseases, Phosphoric Diester Hydrolases, Dietary Fats, Up-Regulation, Diabetes Mellitus, Type 2, Multienzyme Complexes, Phosphodiesterase I, Animals, Humans, Obesity, Insulin Resistance, Lysophospholipids, Pyrophosphatases, Signal Transduction
Male, Prostatic Diseases, Phosphoric Diester Hydrolases, Dietary Fats, Up-Regulation, Diabetes Mellitus, Type 2, Multienzyme Complexes, Phosphodiesterase I, Animals, Humans, Obesity, Insulin Resistance, Lysophospholipids, Pyrophosphatases, Signal Transduction
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