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PubMed Central
Other literature type . 2022
Data sources: PubMed Central
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Journal of Virology
Article . 2022 . Peer-reviewed
Data sources: Crossref
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Omicron: What Makes the Latest SARS-CoV-2 Variant of Concern So Concerning?

Authors: Christoph Jung; Dorota Kmiec; Lennart Koepke; Fabian Zech; Timo Jacob; Konstantin M. J. Sparrer; Frank Kirchhoff;

Omicron: What Makes the Latest SARS-CoV-2 Variant of Concern So Concerning?

Abstract

Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show increased transmission fitness and/or immune evasion are classified as “variants of concern” (VOCs). Recently, a SARS-CoV-2 variant first identified in November 2021 in South Africa has been recognized as a fifth VOC, termed “Omicron.” What makes this VOC so alarming is the high number of changes, especially in the viral Spike protein, and accumulating evidence for increased transmission efficiency and escape from neutralizing antibodies.

Related Organizations
Keywords

Gem, SARS-CoV-2, Mutation, Spike Glycoprotein, Coronavirus, COVID-19, Humans, Genome, Viral, Immune Evasion

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    180
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 0.1%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
180
Top 1%
Top 10%
Top 0.1%
Green