Synthesis of Acerogenin C and (+)-Acerogenin A, Two Macrocyclic Diarylheptanoid Constituents ofAcer nikoense

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1998 English Publisher:WileyJournal:European Journal of Organic Chemistry, volume 1,998, pages 521-524 (issn: 1434-193X, eissn: 1099-0690,

Authors: György Miklós Keserü; Mihály Nógrádi; Áron Szöllösy;

doi: 10.1002/(sici)1099-0690(199803)1998:3<521::aid-ejoc521>3.0.co;2-i

Synthesis of Acerogenin C and (+)-Acerogenin A, Two Macrocyclic Diarylheptanoid Constituents ofAcer nikoense

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Abstract

The macrocyclic ketone acerogenin C (3) and the corresponding alcohol (+)-accerogenin A (1), diarylheptanoid constituents of the maple Acer nikoense were synthesized. The key steps were the selective reduction of the double bond of an α,β-unsaturated ketone (10) and macrocyclization of an iodophenol (13) by a modified Ullmann diarylether synthesis.

Related Organizations

Budapest University of Technology and Economics
Hungary
HUN-REN Research Centre for Natural Sciences
Hungary
Institute of Organic Chemistry
Hungary

14 Research products, page 1 of 2

Cyclic diarylheptanoids as inhibitors of NO production from Acer nikoense
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Studies on the constituents of aceraceae plants. III. Structure of acerogenin B from Acer nikoense Maxim.
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Cyclic diarylheptanoids as Na+-glucose cotransporter (SGLT) inhibitors from Acer nikoense
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ChemInform Abstract: Cyclic Diarylheptanoids as Na⁺‐Glucose Cotransporter (SGLT) Inhibitors from Acer nikoense.
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ChemInform Abstract: Synthesis of Acerogenin C and (.+‐.)‐Acerogenin A, Two Macrocyclic Diarylheptanoid Constituents of Acer nikoense.
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