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Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

Authors: Robyn L. Stanfield; Zachary T. Berndsen; Ruiqi Huang; Devin Sok; Gabrielle Warner; Jonathan L. Torres; Dennis R. Burton; +3 Authors

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

Abstract

Structure and mutagenesis studies show that a potent vaccine-elicited cow bnAb binds with a compact footprint to HIV gp120 CD4bs.

Keywords

Cryoelectron Microscopy, HIV Infections, HIV Antibodies, Antibodies, Viral, Antibodies, Neutralizing, HIV-1, Animals, Cattle, Female, Research Articles, Broadly Neutralizing Antibodies

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    41
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
41
Top 10%
Top 10%
Top 10%
Green
gold