Checks and Balances between Cohesin and Polycomb in Gene Silencing and Transcription
Copyright policy )Checks and Balances between Cohesin and Polycomb in Gene Silencing and Transcription
The cohesin protein complex was discovered for its roles in sister chromatid cohesion and segregation, and the Polycomb group (PcG) proteins for their roles in epigenetic gene silencing during development. Cohesin also controls gene transcription via multiple mechanisms. Genetic and molecular evidence from Drosophila argue that cohesin and the PRC1 PcG complex interact to control transcription of many active genes that are critical for development, and that via these interactions cohesin also controls the availability of PRC1 for gene silencing.
- Saint Louis University United States
- University of Mary United States
- National Institute of Health (NIH/NICHD) United States
- National Institute of Health Pakistan
- National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Development United States
Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Chromosomal Proteins, Non-Histone, Gene Expression Regulation, Developmental, Polycomb-Group Proteins, Cell Cycle Proteins, Drosophila melanogaster, Animals, Drosophila Proteins, Gene Silencing, Cohesins
Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Chromosomal Proteins, Non-Histone, Gene Expression Regulation, Developmental, Polycomb-Group Proteins, Cell Cycle Proteins, Drosophila melanogaster, Animals, Drosophila Proteins, Gene Silencing, Cohesins
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).16 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!